ACTOnco®Pro

Precision Medicine To Orchestrate A Flexible Treatment Strategy

Reveals Comprehensive Strategic Options

In the history of cancer treatment, precision medicine is now endorsed as a modern and preferred way for a healthcare system to take care of its cancer patients. Challenges in identifying the right drug for every cancer patient, as new drugs are emerging for specific genomic mutations, can be tackled strategically by obtaining a cancer patient's unique cancer genomic profile. The acceleration of oncology drug approvals and the modernization of clinical trials with biomarker-based patients have progressed well, as these have been commitments of the USFDA from 2018. The wave of precision medicine has also increased the approvals of companion diagnostics, which has resulted in ACT Genomics' genomic profiling service being on the waiting list for USFDA approval.

Why You Need to Know About Precision Medicine

The top global pharma companies are increasingly conducting clinical trials using precision medicine, which requires a cancer patient's genomic information through genomic profiling. This evolution has been felt by most hospitals, so it is increasingly more likely that genomic profiling will be required if you wish to try a new treatment option.

How to Decide Which Treatment is Better for You?

In life, we may feel regret for a path that was left untaken; however, in cancer treatment, it is important to choose the right path as soon as possible so that there will be no regrets. Although a generic treatment guidance may sometimes provide the correct treatment option, a personalized approach, precision medicine, is much better. The precision medicine approach can assist physicians and patients to confidently navigate the dynamic maze of cancer treatment being directed by genomic mutations, and a study has shown that precision medicine was able to double the percentage of cancer patients who achieved tumor shrinkage. The power of genomics should never be underestimated, as the information contained in the 440 genes associated with cancer has the power to change a patient's life dramatically, as they can identify the right immunotherapy, targeted therapy, chemotherapy or hormonal therapy.

Common Problems Associated with Cancer Treatment

∙ Chemotherapy and surgery are the only options recommended by the NCCN guidelines or single-gene testing results.
∙ Complications and metastases make it difficult to determine an appropriate drug.
∙ Ineffective treatment and cancer relapse after targeted therapy.
∙ Patients lack understanding in immunotherapy and targeted therapy.

Diagnostic Solutions for All Cancers

Through tumor DNA+RNA next-generation sequencing (NGS), ACTOnco^® Pro comprehensive genomic profiling decodes >400 cancer-related genes to map drug options based on thorough clinical research, rather than being limited to a single clinical treatment guideline. ACTOnco^®Pro is able to determine the growth mechanism on a genomic level to provide more treatment strategy options with a higher success rate. ACTOnco^®Pro is suitable for ovarian and breast cancers. As single gene testing only provides very limited results, NGS genomic profiling can detect any special genomic mutations to result in a more effective treatment.

Treatment Advantages from Comprehensive Genomic Profiling 

✔ More humane process: Avoids multiple biopsies and the time cost associated with single-gene testing, as only a small specimen is required for the simultaneous detection of >400 genes.

✔ More ideal treatment: Nominates proper targeted options, immunotherapy, chemotherapy or hormonal therapy.

✔ More intelligent budgeting: Evaluates options before treatment, according to genomic information, to ensure success rate and avoid wasting of funds.

Type of patients
∙ All major solid tumors
∙ Newly diagnosed, advanced, recurrent and metastatic cancer

Specimen requirements 
Tumor tissue (FFPE)

Turnaround time 
10 working days*

*starting from the date of receipt of approved samples at our CAP-accredited laboratory