Lung Cancer
Cancer Type
Tumor Tissue (FFPE) or Blood
Specimen Requirements
2-3 Working Days
Turnaround Time ¹
ACT EGFR™ analyze EGFR gene mutations in cell-free DNA or FFPE DNA for non-small cell lung patients.
Droplet Digital™ PCR technology
7
Alleles
>99%
Analytical Specificity& Sensitivity
0.5%
Limit of Detection
Hallmarks of ACT EGFR™
• Plasma ddPCR detects EGFR mutationrapidly with the high specificityneeded to select therapy and avoid repeat biopsies.
• ddPCR canbe used to detect plasma EGFR gene inadvanced lung adenocarcinoma patients with higher sensitivity andspecificity compared to qPCR.
• ddPCRshowes high concordance with NGS in determiningcfDNA EGFR mutations.
Why using Droplet Digital™ PCR?
• Analyticalspecificity: >99%; Analytical sensitivity: >99%
•Limitof detection:0.5% of mutations in tumor
•Absolutequantification of mutant variants is allowed
• Mutantallele frequency (MAF, %) is reported.*
Summary
Technical Specifications
